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ForumsPharmacology & MechanismsSo the drug literally changes your brain?? That is wild Page 6

So the drug literally changes your brain?? That is wild

tammy_FL Fri, May 15, 2026 at 2:08 AM 26 replies 905 viewsPage 6 of 6
Dr.MetabolicMD
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May 19, 2026 at 3:26 AM#26

From the other side of the consultation, briefly. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

11 11SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 8 others
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COA_Karl
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May 19, 2026 at 1:19 PM#27
Dr.MetabolicMD said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Second this. Nothing to add that would improve it.

10 10jim_asheville, matt_MKE, Dr.ReproEndo and 7 others
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nick_SD_fit
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May 19, 2026 at 11:13 PM#28
Dr.MetabolicMD said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Adding the part of the answer the thread has not reached. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

9 9EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 6 others
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BiostatsBrad
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May 20, 2026 at 9:07 AM#29

The figures, for anyone assembling their own picture. One practical note: write down what you did and when, before you need it. Reconstructing a timeline from memory three months later is how people end up unable to answer the one question that would have resolved it.

8 8james_edin, FranDenver, Dr.BariatricHTX and 5 others
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tammy_FL
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May 20, 2026 at 7:01 PM#30

OP back with an update, since a thread like this is useless without one.

Closing this out: the trough rather than the peak explains the pattern I was seeing on day six, which I had been blaming on the vial.

36 11mike_mealprep, NicoleRaleigh, james_edin and 33 others
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