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ForumsVendor ReviewsI made a spreadsheet comparing vendor COAs — anyone have experience? Page 8

I made a spreadsheet comparing vendor COAs — anyone have experience?

JennaRN Fri, Mar 22, 2024 at 2:29 AM 36 replies 2,800 viewsPage 8 of 8
stefan_berlin
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Apr 29, 2024 at 5:06 PM#36
hyun_seoul said:
It is worth asking what the claim would look like if it were false.

Adding the part of the answer the thread has not reached. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

20 20NeuroNate, JessicaH_TX, KevinCompounds and 17 others
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dan_philly
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May 1, 2024 at 6:07 PM#37

The figures, for anyone assembling their own picture. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

Worth separating that from certificates of analysis, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

Last edited: May 1, 2024 at 9:07 PM
19 19AmyNC_wife, SkepticalSean, Dr.CardioMD and 16 others
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TomTeleRx
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May 3, 2024 at 7:07 PM#38

Following on from hyun_seoul — and this may be the naive question:

What would you measure differently if you were starting again?

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May 5, 2024 at 8:06 PM#39
dan_philly said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

This is where I part company with the consensus forming above. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

Last edited: May 6, 2024 at 12:06 AM
17 17BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 14 others
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BenResearch_OR
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May 7, 2024 at 9:04 PM#40
dan_philly said:
The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

Worth separating that from certificates of analysis, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

45 20PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 42 others
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