Coming back to something from earlier in the thread, because it keeps being talked past:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
A narrower follow-up, since the general answer is now clear:
What did you change at the same time, and can you separate the two now?
Reporting back.
Closing the loop. The answer turned out to depend on the detail I had left out of the opening post, which is a lesson about how to ask rather than about the subject.
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Browse GL BiochemDr.NateNeph said:There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.
Happy to go further on any of that.
Coming back to something from earlier in the thread, because it keeps being talked past:
I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.