[PREMIUM] From wheelchair-bound to hiking again — need advice

mel_PDX said:

Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Plateau breaking story with a stall: I stalled at 207 lbs for 8 weeks. Tried everything — calorie cycling, increased exercise, more water. Nothing worked.

What finally broke the plateau: adding HIIT cardio 2x/week. Lost 10 lbs in the next 3 weeks. Plateaus are temporary — they always break if you stay consistent.

TrialTracker_MD said:

Plateau breaking story with a stall: I stalled at 207 lbs for 8 weeks.

TrialTracker_MD has the substance of this right. The condition it depends on is worth stating. Genuine plateaus happen too, and the mechanism is metabolic adaptation plus a smaller body. A body 20kg lighter needs meaningfully fewer calories at rest and less to move, so the deficit that produced the first phase is arithmetically smaller now. The options are the honest ones — increase the deficit slightly, increase activity, or accept the new plateau — and escalating the dose is only one of them.

mel_PDX said:

Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Same pattern here, and in the same order. I had assumed I was the exception until I read this.

Adding the clinical framing, because it changes how the question reads. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.