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Evidence-based GLP-1 & peptide discussion since 2023
ForumsSide Effects & ManagementHeadaches on GLP-1 — looking for input Page 2

Headaches on GLP-1 — looking for input

robert_kc Wed, Feb 21, 2024 at 11:15 PM 19 replies 2,294 viewsPage 2 of 4
VendorMark
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Feb 22, 2024 at 1:27 AM#6
Dr.AddMedPHL said:
The practical protocol is dull and it works: smaller meals, stop eating at the first sign of fullness rather than at the end of the plate, drop the…

I dislike how confidently this board tells people to push through. Incidence figures around 20 to 25% at the higher doses are class-typical, but the trials also had a discontinuation column, and "manageable with protocols" is not the same as manageable for everyone.

That is the short version; the long version is somebody else's post.

39 9DebRD_ATL, KristenIndy, MarkLI_maint and 36 others
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bri_stats
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Feb 22, 2024 at 2:18 AM#7

Adding the numbers, since they settle part of this. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

38 8mike.trainer_LA, sarah_nash92, FitDadDave and 35 others
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Dr.Martinez
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Feb 22, 2024 at 3:09 AM#8
VendorMark said:
I dislike how confidently this board tells people to push through.

There is a second half to this that has not been said yet. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.

37 7rachel_ABQ, traveltech_sara, AttorneyGrant and 34 others
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KetoKyle
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Feb 22, 2024 at 4:00 AM#9

Following on from jason_sac26 — and this may be the naive question:

Whether holding at a lower dose for longer actually reduces total side-effect burden or just spreads it out?

36 6Dr.GastroMayo, JakeBK_lifts, DerekSJ_a1c and 33 others
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robert_kc
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Feb 22, 2024 at 8:07 AM#10

Reporting back.

Update. It was not the dose, it was that I had stopped drinking anything because drinking made me feel full. Fixing that fixed most of it.

14 12PharmHunterJen, TomTeleRx, DoseLogDan and 11 others
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