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ForumsSide Effects & ManagementNausea incidence by dose tier — my results so far Page 11

Nausea incidence by dose tier — my results so far

MikeFit_NJ Mon, Jul 22, 2024 at 7:15 AM 52 replies 2,374 viewsPage 11 of 11
pete_manc_UK
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Nov 25, 2024 at 4:41 AM#51
wendy_avl said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.

22 20TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 19 others
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rachel_ABQ
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Nov 28, 2024 at 10:29 PM#52
wendy_avl said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Thank you for spelling out the reasoning rather than just the conclusion.

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Dr.LeslieOBGYN
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Dec 2, 2024 at 4:15 PM#53

Clinical perspective, offered as context rather than as advice. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

Last edited: Dec 2, 2024 at 10:15 PM
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ingrid_STO
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Dec 6, 2024 at 9:59 AM#54

Found this through search years later and it is still the best discussion of the question, so adding one thing. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

25 23InsuranceTom, WendyG_ATL, SaraMom3 and 22 others
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mel_PDX
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Dec 10, 2024 at 3:41 AM#55
Dr.LeslieOBGYN said:
It helps to ask what evidence would change your mind before you look at any.

Adding the part of the answer the thread has not reached. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

26 24RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 23 others
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