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ForumsSide Effects & ManagementInsomnia on semaglutide — need advice Page 4

Insomnia on semaglutide — need advice

wei_SG Tue, Dec 17, 2024 at 5:21 AM 34 replies 1,822 viewsPage 4 of 7
pete_nash
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Dec 21, 2024 at 7:02 AM#16

Adding the clinical framing, because it changes how the question reads. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

Last edited: Dec 21, 2024 at 1:02 PM
16 14Admin, Dr.Martinez, mike_mod and 13 others
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marcus_mpls
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Dec 21, 2024 at 9:48 AM#17
pete_nash said:
It is worth asking what the claim would look like if it were false.

I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.

17 15oliver_london, tane_welly, Dr.PathRoch and 14 others
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oliver_london
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Dec 21, 2024 at 12:34 PM#18
pete_nash said:
It is worth asking what the claim would look like if it were false.

Agreeing with pete_nash, and the qualification matters more than the agreement. Steady state is the thing most people miss. The terminal half-life is about a week, so every dose step takes four to five weeks to fully express itself. Judging a step at day ten is judging the ascent, not the plateau, and it is the single commonest reason people escalate before they needed to.

Last edited: Dec 21, 2024 at 1:34 PM
18 16Dr.LeslieOBGYN, MikeNYC_runner and 15 others
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Dr.GastroMayo
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Dec 21, 2024 at 3:20 PM#19
pete_nash said:
It is worth asking what the claim would look like if it were false.

Bookmarking. The distinction being drawn above is the one nobody else makes. Adding it to my notes with a link back to this thread.

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Admin
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Dec 21, 2024 at 6:06 PM#20

Moderator note: the sourcing question belongs in the vendor section and has been split out.

41 14PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 38 others
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