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ForumsMASH / Liver DiseaseNon-invasive MASH biomarkers — March 2026 Page 3

Non-invasive MASH biomarkers — March 2026

AttorneyGrant Thu, Feb 8, 2024 at 1:03 AM 54 replies 3,138 viewsPage 3 of 11
pete_manc_UK
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Feb 10, 2024 at 8:40 PM#11
Dr.RenalNash said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

42 15TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 39 others
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fiona_VT
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Feb 13, 2024 at 9:17 AM#12
anders_CPH said:
ATTAIN trial (survodutide) context for liver and MASH: survodutide, a GLP-1/glucagon dual agonist, showed -18.7% body weight at 46 weeks in the Phase…

This answered a question I did not know how to ask. Adding it to my notes with a link back to this thread.

Last edited: Feb 13, 2024 at 10:17 AM
43 16hans_munich, jason_sac26, chris_chi24 and 40 others
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mike_mealprep
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Feb 15, 2024 at 9:53 PM#13
Dr.RenalNash said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

This is where I part company with the consensus forming above. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

44 17Dr.AddMedPHL, newstart_MO, mia_MS2 and 41 others
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dave_SLC
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Feb 18, 2024 at 10:28 AM#14

Adding the numbers, since they settle part of this. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

45 18FranDenver, Dr.BariatricHTX, LindaRN_retired and 42 others
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Admin
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Feb 20, 2024 at 11:01 PM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again.

Last edited: Feb 21, 2024 at 3:01 AM
46 19PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 43 others
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