Kidney stone risk on GLP-1 — my results so far

TrialTracker_MD said:

There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Coming at TrialTracker_MD’s question from a different direction. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

One thing that is still open after TrialTracker_MD’s answer:

How long did you give it before you decided it was working?

Dr.RaviCardio said:

Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

Dr.RaviCardio said:

Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.