My liver enzyme journey — looking for input

PeptideChemSF said:

Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Coming at PeptideChemSF’s question from a different direction. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

The figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

I would rather be corrected than agreed with, if it comes to it.

Following on from PeptideChemSF — and this may be the naive question:

What would you measure differently if you were starting again?

DanielChem_CHI said:

If you are going to change something, change one thing and give it long enough to express itself.

Pushing back on DanielChem_CHI here. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

OP back with an update, since a thread like this is useless without one.

For the archive: it took about six weeks rather than the two I expected, and the difference between those two numbers was the whole of my problem.