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ForumsMASH / Liver DiseaseMy liver enzyme journey — looking for input Page 3

My liver enzyme journey — looking for input

Dr.KarenChen Tue, Jul 9, 2024 at 5:54 PM 39 replies 2,351 viewsPage 3 of 8
nick_newbie
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Jul 10, 2024 at 5:32 AM#11
Dr.RheumBOS said:
Liver enzyme update related to liver and MASH: I had mildly elevated ALT/AST at baseline (likely NAFLD).

Genuinely useful, thank you. I had the facts and not the framework. Adding it to my notes with a link back to this thread.

25 23robert_kc, dan_philly, MeganSA_TX and 22 others
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LindaRN_retired
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Jul 10, 2024 at 8:19 AM#12

From the other side of the consultation, briefly. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

Correct me if the detail matters more than I have assumed.

26 24Dr.GutHealth, amsterdam_pete, LondonLisa and 23 others
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PharmD_Rodriguez
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Jul 10, 2024 at 11:06 AM#13
Dr.SurgeonPGH said:
NASH/MAFLD therapeutic landscape and liver and MASH: GLP-1 agonists are emerging as potential first-line NASH therapy.

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

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PeptideChemSF
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Jul 10, 2024 at 1:53 PM#14

Adding the numbers, since they settle part of this. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

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mike_mod
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Jul 10, 2024 at 4:40 PM#15

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. No action needed from anybody.

Last edited: Jul 10, 2024 at 6:40 PM
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