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ForumsExercise & Body CompositionRecovery optimization on GLP-1 — need advice

Recovery optimization on GLP-1 — need advice

MarkLI_maint Thu, May 16, 2024 at 12:55 PM 8 replies 1,913 viewsPage 1 of 2
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MarkLI_maint
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May 16, 2024 at 12:55 PM#1

I lifted three times a week throughout and still lost lean mass. Not as much as I expected to, but the idea that training prevents it entirely is not what my scan says.

If you are tracking this properly: same scanner, same time of day, same hydration, at least six months apart, and read grip strength or a lift number alongside it. Function is the outcome; the scan is the proxy.

What I actually want to know is whether resistance training and protein change the ratio or only the absolute amount.

Not looking for reassurance. Looking for the part I have got wrong.

49 19RunnerRach, TrialNerd_Beth, HPLC_Greg and 46 others
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Dr.SportsMedIN
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May 16, 2024 at 1:07 PM#2

Short answer first, then the reasoning. There is also a quality change that the scan cannot see. Weight loss shifts fiber-type distribution toward Type I and improves mitochondrial density and insulin-stimulated glucose uptake per fiber — so the muscle you keep is metabolically better even though there is less of it. That does not make the loss irrelevant, but it explains why function often holds up better than the number suggests.

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anna.melb_AU
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May 16, 2024 at 1:19 PM#3
Dr.SportsMedIN said:
There is also a quality change that the scan cannot see.

Right, and protein targets should be set on a reference weight rather than current weight. Setting 1.6 g/kg on a starting weight of 130kg produces a target nobody hits on a suppressed appetite.

47 17emma_london, tammy_FL, Dr.LipidDallas and 44 others
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SleepFixSam
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May 16, 2024 at 1:31 PM#4
MarkLI_maint said:
I lifted three times a week throughout and still lost lean mass.

Can confirm the pattern MarkLI_maint describes. The intervention that works is boring and well evidenced: resistance training two to three times a week at a genuine effort, protein at 1.4 to 2.0 g/kg of reference body weight, and not making the deficit larger than the training can support. Cardio does not protect lean mass and in a deep deficit competes with recovery.

Last edited: May 16, 2024 at 3:31 PM
46 16denise_HTX, raj_cambridge, ingrid_STO and 43 others
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Dr.SleepRoch
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May 16, 2024 at 2:36 PM#5

Adding the clinical framing, because it changes how the question reads.

DEXA scan update relevant to lean mass:

Scanned at months 0, 6, and 12. Here are the body comp numbers:

BaselineMonth 6Month 12
Total mass251 lbs221 lbs198 lbs
Fat mass101 lbs71 lbs48 lbs
Lean mass154 lbs150 lbs155 lbs
Body fat %44%30%22%

Lean mass preserved — actually GAINED 1-2 lbs thanks to progressive overload + 1.4g/kg protein. The lean mass discussion needs to include body comp data, not just scale weight.

Last edited: May 16, 2024 at 6:36 PM
45 15roxy_nash, tony_orlando, Dr.NephBHM_UK and 42 others
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