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ForumsProgress & Lab Results[PREMIUM] DEXA before/after — anyone have experience? Page 3

[PREMIUM] DEXA before/after — anyone have experience?

PeptideSynthNJ Thu, Sep 18, 2025 at 7:59 AM 47 replies 1,788 viewsPage 3 of 10
labquiet_amy
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Sep 20, 2025 at 2:16 PM#11
PedsEndoPhilly said:
Bone density monitoring on lean mass: DEXA bone density at baseline and month 12.

Sharing my comprehensive lab data relevant to lean mass:

BiomarkerBaselineMonth 3Month 6Month 9
Weight (lbs)281256221211
A1C (%)7.66.16.25.3
hsCRP (mg/L)6.05.02.50.7
Triglycerides241181141101

Protocol: Tirzepatide 10mg/wk, resistance training 5x/week, protein 1.5g/kg/day.

The improvements in lean mass are clearly reflected in these numbers. The inflammatory marker reduction (hsCRP) is particularly striking.

38 11TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 35 others
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anna.melb_AU
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Sep 21, 2025 at 10:33 AM#12
mike_mealprep said:
Right, and protein targets should be set on a reference weight rather than current weight.

Thank you for spelling out the reasoning rather than just the conclusion. Adding it to my notes with a link back to this thread.

39 12paige_pharma, emma_london, tammy_FL and 36 others
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DebRD_ATL
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Sep 22, 2025 at 6:49 AM#13
PedsEndoPhilly said:
Bone density monitoring on lean mass: DEXA bone density at baseline and month 12.

Physical therapist weighing in on lean mass. I work with bariatric and metabolic patients daily.

The resistance training evidence is critical here:

The Lundgren 2024 JAMA paper[1] showed that structured resistance training preserved 73% more lean mass in GLP-1 patients vs medication alone. When discussing lean mass, we MUST include the exercise component.

My minimum prescription: 3x/week compound movements (squat, deadlift, press, row), progressive overload, 7-10K steps/day, and 1.2-1.6g protein/kg/day.

References:
[1] Lundgren JR, et al. JAMA. 2024;331(1):38-48.
40 13SleepDoc_PDX, RegAffairsDC, BiostatsBrad and 37 others
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josh_phd_bmore
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Baltimore, MD
Sep 23, 2025 at 3:05 AM#14
PeptideSynthNJ said:
I lifted three times a week throughout and still lost lean mass.

Body composition tracking via bioimpedance on lean mass (InBody scan every 3 months):

MetricBaselineMonth 3Month 6Month 9
Skeletal Muscle (lbs)69676871
Body Fat (lbs)96755341
Body Fat %39%32%26%21%
Visceral Fat (cm²)1461118156

Note: skeletal muscle mass dipped initially then recovered with consistent resistance training + high protein. The visceral fat reduction is where the metabolic magic happens.

41 14KarenAZ_mom, zoe_NC, Dr.ObesityLA and 38 others
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Admin
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Sep 23, 2025 at 11:20 PM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Carry on.

42 15PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 39 others
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