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ForumsMASH / Liver DiseaseSurvodutide SYNCHRONIZE Phase 3 — November 2025 Page 9

Survodutide SYNCHRONIZE Phase 3 — November 2025

ZaraB_AL Thu, Sep 12, 2024 at 4:18 AM 56 replies 2,243 viewsPage 9 of 12
KristenIndy
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Feb 18, 2025 at 5:09 PM#41
PharmHunterJen said:
Start from the measurement rather than the conclusion.

There is a second half to this that has not been said yet. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

47 20LondonLisa, mike_nyc, VendorMark and 44 others
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Dr.GutHealth
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Feb 25, 2025 at 2:16 PM#42

The figures, for anyone assembling their own picture. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

48 21tyler_CSCS, VanRx_Mike, steve_okc and 45 others
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mike_mod
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Mar 4, 2025 at 11:19 AM#43

Moderator note: a couple of off-topic posts removed.

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LondonLisa
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Mar 11, 2025 at 8:18 AM#44
Dr.GutHealth said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

I read this differently from Dr.GutHealth, on substance rather than tone. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.

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NurseLeah_Nash
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Mar 18, 2025 at 5:13 AM#45
Dr.GutHealth said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.

That is the short version; the long version is somebody else's post.

1 24Dr.NateNeph
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