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ForumsMASH / Liver DiseaseHas anyone dealt with mash resolution without worsening fibrosis? Page 3

Has anyone dealt with mash resolution without worsening fibrosis?

KevinCompounds Thu, Oct 31, 2024 at 11:40 AM 45 replies 2,606 viewsPage 3 of 9
TrialNerd_Beth
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Nov 2, 2024 at 12:43 AM#11
hyun_seoul said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.

37 10RickReta_CO, PharmHunterJen, TomTeleRx and 34 others
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VanRx_Mike
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Nov 2, 2024 at 2:58 AM#12
carlos_SATX said:
Liver enzyme update related to liver and MASH: I had mildly elevated ALT/AST at baseline (likely NAFLD).

That reframing is the part I needed. I will report back once I have actually tried it.

Last edited: Nov 2, 2024 at 5:58 AM
38 11MikeNYC_runner and 35 others
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Dr.CardioMD
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Nov 2, 2024 at 5:13 AM#13
hyun_seoul said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

Last edited: Nov 2, 2024 at 11:13 AM
39 12tony_orlando, Dr.NephBHM_UK, kim_atl_prep and 36 others
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dave_SLC
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Nov 2, 2024 at 7:29 AM#14

Adding the numbers, since they settle part of this. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

40 13FranDenver, Dr.BariatricHTX, LindaRN_retired and 37 others
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mike_mod
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Nov 2, 2024 at 9:45 AM#15

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Report rather than reply if it drifts again.

Last edited: Nov 2, 2024 at 11:45 AM
41 14PurityPaulOR, MaxMetOK, MounjBrad and 38 others
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