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ForumsSide Effects & ManagementAnyone else get weird vivid dreams on sema?? — looking for input Page 2

Anyone else get weird vivid dreams on sema?? — looking for input

LeilaHI Sun, Aug 24, 2025 at 8:19 PM 13 replies 1,432 viewsPage 2 of 3
Dr.GastroMayo
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Aug 25, 2025 at 2:12 AM#6
BariatricNurseD said:
The practical protocol is dull and it works: smaller meals, stop eating at the first sign of fullness rather than at the end of the plate, drop the…

I dislike how confidently this board tells people to push through. Incidence figures around 20 to 25% at the higher doses are class-typical, but the trials also had a discontinuation column, and "manageable with protocols" is not the same as manageable for everyone.

5 0mike_nyc, VendorMark, COA_Karl and 2 others
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DataDave
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Aug 25, 2025 at 4:31 AM#7

Adding the numbers, since they settle part of this. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

4 24mike_nyc, VendorMark, COA_Karl and 1 other
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NurseLeah_Nash
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Aug 25, 2025 at 6:50 AM#8
Dr.GastroMayo said:
I dislike how confidently this board tells people to push through.

Adding the part of the answer the thread has not reached. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

Last edited: Aug 25, 2025 at 7:50 AM
3 23PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph
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GenomicsKate
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Aug 25, 2025 at 9:09 AM#9

One thing that is still open after nick_newbie’s answer:

What distinguishes the nausea you can titrate through from the nausea that means stop?

2 22Dr.PeteFamMed, claudia_zurich
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LeilaHI
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Aug 25, 2025 at 8:17 PM#10

OP back with an update, since a thread like this is useless without one.

Holding the step for six weeks instead of four did it. Same dose, same food, and the nausea that had felt like a wall turned out to be a timing problem.

Last edited: Aug 26, 2025 at 1:17 AM
14 12amsterdam_pete, LondonLisa, mike_nyc and 11 others
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