Writing this once so I can stop repeating it across threads. It is about alcohol, and it is deliberately narrow — everything I am not confident about is marked as such.
What is actually established
Reduced interest in alcohol is one of the most consistently reported off-target effects, and the mechanism is plausibly the same reward-salience pathway that quiets food noise. The practical part people get wrong is that tolerance changes: less food in the stomach, faster gastric emptying of liquid relative to solids, and a smaller body mean the same two drinks land considerably harder than they used to.
The condition it depends on
If the change has opened a harder question about someone's drinking, that belongs with a service rather than a thread.
What I am not sure about
What I actually want to know is whether the change in tolerance is the smaller stomach, the smaller body, or something central, and whether it settles. Practical detail welcome, however dull — the duller the better.
— DanielChem_CHI · corrections welcome and will be edited into this post with credit