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ForumsSemaglutide (Ozempic / Wegovy)Skin elasticity changes during sema weight loss — 12 month update Page 3

Skin elasticity changes during sema weight loss — 12 month update

quinn_sf Thu, May 2, 2024 at 11:40 PM 13 replies 1,993 viewsPage 3 of 3
DebRD_ATL
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May 8, 2024 at 4:37 PM#11
Dr.MetabolicMD said:
The version of this that has an answer is narrower than the version being asked.

All true, with one condition: that curve is for people who reached the dose on schedule. Anyone who slowed the ladder for tolerability is on a different, flatter curve, and comparing yourself with the published mean will make you feel like a non-responder when you are not.

19 17BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 16 others
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andrew_nyc
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May 9, 2024 at 8:18 AM#12
TomTeleRx said:
The mechanism that matters here is not stomach emptying, it is central.

This answered a question I did not know how to ask. Taking it to my next appointment.

Last edited: May 9, 2024 at 1:18 PM
20 18Dr.NateNeph, PharmD_Rodriguez, julia.endo and 17 others
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B12Beth
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May 9, 2024 at 11:59 PM#13
Dr.MetabolicMD said:
The version of this that has an answer is narrower than the version being asked.

I will push back on the "any working dose is fine" framing. The maintenance evidence sits overwhelmingly at the top studied dose, and the extension data shows regain tracking dose reduction rather than tracking stopping. Holding low is reasonable; pretending it is evidentially equivalent is not.

21 19DanielChem_CHI, marco_milano, pam_columbus and 18 others
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FDA_TrackerJim
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May 10, 2024 at 3:39 PM#14

The figures, for anyone assembling their own picture. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

22 20Dr.LeslieOBGYN, MikeNYC_runner and 19 others
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mike_mod
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May 11, 2024 at 7:19 AM#15

Moderator note: a couple of off-topic posts removed.

Last edited: May 11, 2024 at 9:19 AM
23 21PurityPaulOR, MaxMetOK, MounjBrad and 20 others
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