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ForumsProgress & Lab Results1-year semaglutide anniversary — anyone have experience? Page 4

1-year semaglutide anniversary — anyone have experience?

oliver_london Fri, Jan 9, 2026 at 10:47 PM 24 replies 1,368 viewsPage 4 of 5
PeptideChemSF
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Jan 14, 2026 at 4:08 PM#16

Clinical perspective, offered as context rather than as advice. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

Correct me if the detail matters more than I have assumed.

14 12steve_okc, dave_SLC, FDA_TrackerJim and 11 others
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gary_naperville
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Jan 15, 2026 at 12:19 AM#17
PeptideChemSF said:
Worth answering the question that was asked rather than the one behind it.

Same pattern here, and in the same order. Posting only so the count is not one.

15 13DoseLogDan, SleepFixSam, PurityPaulOR and 12 others
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AttorneyGrant
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Jan 15, 2026 at 8:30 AM#18
PeptideChemSF said:
Worth answering the question that was asked rather than the one behind it.

Coming at PeptideChemSF’s question from a different direction. The dose-response is real but shallow at the top. Across STEP 1 and STEP 4 the gap between 1.7mg and 2.4mg is a couple of percentage points of body weight on average, and the average is carrying a wide spread — plenty of people at 1.7mg sit above the 2.4mg mean. If a dose is working and tolerable, "working" is the relevant variable, not "maximal".

I would rather be corrected than agreed with, if it comes to it.

16 14JenMemphis, pat_auckland, Dr.GastroMayo and 13 others
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Dr.PeteFamMed
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Jan 15, 2026 at 4:41 PM#19

The figures, for anyone assembling their own picture. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

17 15Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 14 others
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Admin
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Jan 16, 2026 at 12:52 AM#20

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again.

39 12PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 36 others
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