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ForumsSide Effects & ManagementInsomnia on semaglutide — anyone have experience? Page 5

Insomnia on semaglutide — anyone have experience?

hyun_seoul Tue, Nov 11, 2025 at 7:44 AM 29 replies 1,343 viewsPage 5 of 6
HPLC_Greg
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Nov 14, 2025 at 12:17 PM#21

The figures, for anyone assembling their own picture. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

24 22SallyK_inj, CryptoCarl, MariaRD and 21 others
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JessicaH_TX
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Nov 15, 2025 at 9:28 AM#22

A narrower follow-up, since the general answer is now clear:

Whether anyone has held at a sub-maximal dose long term and kept the result, or whether the maintenance data only exists at 2.4mg?

Last edited: Nov 15, 2025 at 1:28 PM
25 23sarah_TO, wendy_avl, jason_paloalto and 22 others
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LindaRN_retired
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Nov 16, 2025 at 6:39 AM#23
HPLC_Greg said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

26 24amsterdam_pete, LondonLisa, mike_nyc and 23 others
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COA_Karl
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Nov 17, 2025 at 3:49 AM#24
HPLC_Greg said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.

Last edited: Nov 17, 2025 at 4:49 AM
27 0tommy_boulder, hyun_seoul, jim_asheville and 24 others
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gary_naperville
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Nov 18, 2025 at 12:59 AM#25
HPLC_Greg said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Thank you for spelling out the reasoning rather than just the conclusion. Adding it to my notes with a link back to this thread.

28 1RickReta_CO, PharmHunterJen, TomTeleRx and 25 others
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