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ForumsSemaglutide (Ozempic / Wegovy)Oral semaglutide 25mg vs 50mg — looking for input Page 9

Oral semaglutide 25mg vs 50mg — looking for input

pam_stl Thu, May 30, 2024 at 9:03 AM 55 replies 2,751 viewsPage 9 of 11
nancy_portland
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Jun 20, 2024 at 5:26 PM#41
stefan_berlin said:
For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.

This is exactly what I could not find anywhere else. I will report back once I have actually tried it.

Last edited: Jun 20, 2024 at 6:26 PM
24 22DebRD_ATL, KristenIndy, MarkLI_maint and 21 others
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Dr.EndoEP
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Jun 21, 2024 at 12:58 PM#42

From the other side of the consultation, briefly. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.

25 23james_edin, FranDenver, Dr.BariatricHTX and 22 others
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mike_mod
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Jun 22, 2024 at 8:29 AM#43

Moderator note: the sourcing question belongs in the vendor section and has been split out. Report rather than reply if it drifts again.

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MarkLI_maint
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Jun 23, 2024 at 4:00 AM#44
Dr.EndoEP said:
The useful move here is to separate what is established from what is widely repeated.

There is a second half to this that has not been said yet. The dose-response is real but shallow at the top. Across STEP 1 and STEP 4 the gap between 1.7mg and 2.4mg is a couple of percentage points of body weight on average, and the average is carrying a wide spread — plenty of people at 1.7mg sit above the 2.4mg mean. If a dose is working and tolerable, "working" is the relevant variable, not "maximal".

Last edited: Jun 23, 2024 at 9:00 AM
27 0LibrarianMeg, bri_stats, pete_manc_UK and 24 others
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dan_philly
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Jun 23, 2024 at 11:30 PM#45

The figures, for anyone assembling their own picture. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

I would rather be corrected than agreed with, if it comes to it.

Last edited: Jun 24, 2024 at 2:30 AM
28 1EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 25 others
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