anders_CPH said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.
RickReta_CO said:The mechanism is more central than most summaries suggest.
Saving this. It is the first explanation that did not require me to already understand it. Taking it to my next appointment.
anders_CPH said:PK/PD modeling for the pharmacology: understanding the pharmacokinetics helps optimize dosing.
I read this differently from anders_CPH, on substance rather than tone. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
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Browse GL BiochemAdding the numbers, since they settle part of this. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.
Moderator note: the sourcing question belongs in the vendor section and has been split out. Thread quality here is what the rules are for. Keep it up.