Pilates for core strength during GLP-1 weight loss — what worked for you?

anna.melb_AU said:

DEXA scan update relevant to lean mass: Scanned at months 0, 6, and 12.

Body composition tracking via bioimpedance on lean mass (InBody scan every 3 months):

Note: skeletal muscle mass dipped initially then recovered with consistent resistance training + high protein. The visceral fat reduction is where the metabolic magic happens.

anders_CPH said:

Right, and protein targets should be set on a reference weight rather than current weight.

Bookmarking. The distinction being drawn above is the one nobody else makes.

anna.melb_AU said:

DEXA scan update relevant to lean mass: Scanned at months 0, 6, and 12.

Regarding lean mass: I accidentally injected my dose intramuscularly instead of subcutaneously last week (went in at wrong angle, too deep). Called my pharmacist — they said it's not dangerous but may absorb faster, potentially causing more GI effects.

Sure enough, had worse nausea that day. Lesson learned: pinch the skin properly and use the right needle length for your body composition.

Dr.RheumBOS said:

Two DEXA scans eleven months apart: down 24kg total, of which the scan says 6kg was lean.

Muscle fiber type changes during GLP-1-mediated weight loss, relevant to lean mass: preliminary biopsy data suggests that weight loss shifts the skeletal muscle fiber type distribution:

• Decreased Type IIx (glycolytic, fast-twitch) fibers
• Increased Type I (oxidative, slow-twitch) fibers
• Improved mitochondrial density and function
• Enhanced insulin-stimulated glucose uptake per fiber

This "metabolic remodeling" of muscle may contribute to improved insulin sensitivity independent of total lean mass changes. The muscle you keep becomes metabolically better, even if there's less of it[1].

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