Dr.LipidDallas said:ChrisMacros said: ...but the FDA says semaglutide...
Agreed, and ALT falling is not the same as fibrosis improving. Enzymes are a crude proxy; FIB-4 or elastography is what tells you about the thing that matters.
Ask again with the specifics and you will get a better answer than this one.
stefan_berlin said:Agreed, and ALT falling is not the same as fibrosis improving.
This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.
stefan_berlin said:Agreed, and ALT falling is not the same as fibrosis improving.
That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.
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Browse GL Biochemstefan_berlin said:Agreed, and ALT falling is not the same as fibrosis improving.
Thank you — that is the clearest version of this I have read, and I have read a lot of them. Sending this to two other people who asked me the same thing last week.
Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Carry on.