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ForumsOther Peptides & Research CompoundsBPC-157 systemic vs local effects — September 2026 Page 6

BPC-157 systemic vs local effects — September 2026

SleepFixSam Fri, Oct 18, 2024 at 7:05 PM 35 replies 2,053 viewsPage 6 of 7
stefan_berlin
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Oct 2024
Berlin, DE
Oct 25, 2024 at 7:16 AM#26

One thing that is still open after NurseLeah_Nash’s answer:

What did you change at the same time, and can you separate the two now?

3 1NeuroNate, JessicaH_TX, KevinCompounds
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TrialTracker_MD
Senior Member
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15,678
Jan 2024
Maryland
Oct 25, 2024 at 8:47 PM#27
Dr.NateNeph said:
Practical: whatever you change, write down the date and the reason.

I read this differently from Dr.NateNeph, on substance rather than tone. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

4 2stefan_berlin, Dr.EM_Chicago, pete_RVA and 1 other
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emily_PDX
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Nov 2024
Portland, OR
Oct 26, 2024 at 10:18 AM#28
Dr.NateNeph said:
Practical: whatever you change, write down the date and the reason.

Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.

5 3Dr.NateNeph, PharmD_Rodriguez, julia.endo and 2 others
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rachel_ABQ
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Dec 2024
Albuquerque, NM
Oct 26, 2024 at 11:49 PM#29
Dr.NateNeph said:
Practical: whatever you change, write down the date and the reason.

Thank you — that is the clearest version of this I have read, and I have read a lot of them.

Last edited: Oct 27, 2024 at 4:49 AM
6 4SkepticalSean, Dr.CardioMD, EndoResFellow and 3 others
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SleepFixSam
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Nov 2024
Hawaii
Oct 27, 2024 at 1:19 PM#30

OP back with an update, since a thread like this is useless without one.

Update — tachyphylaxis to the gastric effect, persistence of the appetite effect. Two curves, and I had been watching the wrong one.

28 1fiona_VT, denise_HTX, raj_cambridge and 25 others
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