Clinical perspective, offered as context rather than as advice. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.
A narrower follow-up, since the general answer is now clear:
What would you measure differently if you were starting again?
TrialTracker_MD said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
This is where I part company with the consensus forming above. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.
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Browse GL BiochemTrialTracker_MD said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.