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Evidence-based GLP-1 & peptide discussion since 2023
ForumsSide Effects & ManagementI literally cannot eat more than 3 bites help Page 2

I literally cannot eat more than 3 bites help

WendyG_ATL Tue, Apr 21, 2026 at 2:19 AM 11 replies 719 viewsPage 2 of 3
COA_Karl
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Apr 22, 2026 at 11:22 AM#6
NeuroNate said:
The practical protocol is dull and it works: smaller meals, stop eating at the first sign of fullness rather than at the end of the plate, drop the…

I dislike how confidently this board tells people to push through. Incidence figures around 20 to 25% at the higher doses are class-typical, but the trials also had a discontinuation column, and "manageable with protocols" is not the same as manageable for everyone.

That is the short version; the long version is somebody else's post.

38 8matt_MKE, Dr.ReproEndo, lucas_SP_BR and 35 others
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BiostatsBrad
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Apr 23, 2026 at 12:35 AM#7

Adding the numbers, since they settle part of this. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

37 7Dr.BariatricHTX, LindaRN_retired, tommy_boulder and 34 others
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Dr.DermMIA
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Miami, FL
Apr 23, 2026 at 1:48 PM#8
COA_Karl said:
I dislike how confidently this board tells people to push through.

Coming at COA_Karl’s question from a different direction. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

36 6A1cHero_PHX, Dr.RenalNash, LipidDoc_ATL and 33 others
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JakeSmashed95
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Apr 24, 2026 at 3:01 AM#9

One thing that is still open after NurseKim_ATL’s answer:

What distinguishes the nausea you can titrate through from the nausea that means stop?

35 5Dr.LipidDallas, alex_tucson, kevin_tulsa and 32 others
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WendyG_ATL
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Apr 2024
Georgia
Apr 26, 2026 at 6:30 PM#10

Reporting back.

Holding the step for six weeks instead of four did it. Same dose, same food, and the nausea that had felt like a wall turned out to be a timing problem.

21 19DebRD_ATL, KristenIndy, MarkLI_maint and 18 others
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