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ForumsMASH / Liver DiseaseGLP-1 hepatoprotection — looking for input Page 3

GLP-1 hepatoprotection — looking for input

emma_london Sat, Jan 3, 2026 at 5:22 PM 32 replies 1,569 viewsPage 3 of 7
tony_orlando
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Jan 4, 2026 at 11:00 AM#11
anders_CPH said:
NASH/MAFLD therapeutic landscape and liver and MASH: GLP-1 agonists are emerging as potential first-line NASH therapy.

Thank you for spelling out the reasoning rather than just the conclusion.

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Dr.RenalNash
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Jan 4, 2026 at 1:13 PM#12

From the other side of the consultation, briefly. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

Last edited: Jan 4, 2026 at 6:13 PM
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BariatricNurseD
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Jan 4, 2026 at 3:26 PM#13
CarlaRPh_TPA said:
Liver enzyme update related to liver and MASH: I had mildly elevated ALT/AST at baseline (likely NAFLD).

This is where I part company with the consensus forming above. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

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Dr.RaviCardio
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Jan 4, 2026 at 5:39 PM#14

One concrete data point for the thread. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

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mike_mod
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Jan 4, 2026 at 7:52 PM#15

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Thread quality here is what the rules are for. Keep it up.

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