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ForumsSemaglutide (Ozempic / Wegovy)Semaglutide and alcohol intolerance — my results so far Page 4

Semaglutide and alcohol intolerance — my results so far

TrialNerd_Beth Wed, Sep 10, 2025 at 9:36 PM 22 replies 1,672 viewsPage 4 of 5
kevin_tulsa
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Sep 12, 2025 at 4:31 PM#16
Dr.RheumBOS said:
TrialNerd_Beth said: ...but the FDA says semaglutide...

Agreed, and if the change has opened a harder question about someone's drinking, that belongs with a service rather than a thread.

Last edited: Sep 12, 2025 at 6:31 PM
31 4fiona_glasgow, Dr.RheumBOS, greg_boulder and 28 others
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lisa_labSD
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Sep 12, 2025 at 8:11 PM#17

Adding the clinical framing, because it changes how the question reads. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

32 5maya_sedona, stefan_berlin, Dr.EM_Chicago and 29 others
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Admin
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Sep 12, 2025 at 11:51 PM#18
lisa_labSD said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Mine went the same way, slower.

33 6RegAffairsDC, BiostatsBrad, PeptideSynthNJ and 30 others
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pam_columbus
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Sep 13, 2025 at 3:31 AM#19
lisa_labSD said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

There is a second half to this that has not been said yet. Reduced interest in alcohol is one of the most consistently reported off-target effects, and the mechanism is plausibly the same reward-salience pathway that quiets food noise. The practical part people get wrong is that tolerance changes: less food in the stomach, faster gastric emptying of liquid relative to solids, and a smaller body mean the same two drinks land considerably harder than they used to.

Last edited: Sep 13, 2025 at 9:31 AM
34 7tammy_FL, Dr.LipidDallas, alex_tucson and 31 others
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NurseKim_ATL
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Sep 13, 2025 at 7:11 AM#20

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Carry on.

Last edited: Sep 13, 2025 at 12:11 PM
6 4hank_denver, carlos_SATX, sophie_paris and 3 others
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