One concrete data point for the thread. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.
One thing that is still open after NurseAsh_DET’s answer:
Whether holding at a lower dose for longer actually reduces total side-effect burden or just spreads it out?
Dr.NateNeph said:For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine.
There is a second half to this that has not been said yet. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
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Browse GL BiochemOP back with an update, since a thread like this is useless without one.
Follow-up: smaller meals, less fat in the two days after dosing, and not lying down afterwards. Unglamorous, and it worked within a fortnight.
Dr.RaviCardio said:The mechanism and the magnitude are separate questions.
Agreeing with Dr.RaviCardio, and the qualification matters more than the agreement. The meal advice is right and incomplete without the hydration point. People stop drinking because drinking makes them feel full, then attribute dehydration symptoms to the drug.