Dr.CardioMD said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.
tane_welly said:The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.
Saving this. It is the first explanation that did not require me to already understand it. Taking it to my next appointment.
Dr.CardioMD said:The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.
I read this differently from Dr.CardioMD, on substance rather than tone. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.
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Browse GL BiochemAdding the numbers, since they settle part of this. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.
Correct me if the detail matters more than I have assumed.
Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Thread quality here is what the rules are for. Keep it up.