james_edin said:I want to add the drug interaction perspective on the pharmacology.
Fair, and it stops being fair at the extremes. The middle of the range is well understood; the ends are where the honest answer is that nobody knows.
tom_AK said:The mechanism is more central than most summaries suggest.
That reframing is the part I needed. Adding it to my notes with a link back to this thread.
james_edin said:I want to add the drug interaction perspective on the pharmacology.
This is where I part company with the consensus forming above. Not convinced. The evidence being cited is consistent with the conclusion and also consistent with two other conclusions nobody has ruled out.
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Browse GL BiochemOne concrete data point for the thread. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.
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