DanielChem_CHI said:Practical: whatever you change, write down the date and the reason.
That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.
DanielChem_CHI said:Practical: whatever you change, write down the date and the reason.
Thank you for spelling out the reasoning rather than just the conclusion. Adding it to my notes with a link back to this thread.
From the other side of the consultation, briefly. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.
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Browse GL BiochemMASHdoc_SA said:If two explanations both fit, the useful question is which one predicts something the other does not.
Mine went the same way, slower. The detail I would add is minor and it is already implied above.
MASHdoc_SA said:If two explanations both fit, the useful question is which one predicts something the other does not.
Coming at MASHdoc_SA’s question from a different direction. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.