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ForumsSemaglutide (Ozempic / Wegovy)0.25mg → 2.4mg titration: optimal schedule based on clinical data — looking for input Page 7

0.25mg → 2.4mg titration: optimal schedule based on clinical data — looking for input

anders_CPH Mon, Feb 2, 2026 at 2:28 AM 33 replies 1,047 viewsPage 7 of 7
wendy_avl
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Asheville, NC
Mar 31, 2026 at 1:45 AM#31
raj_cambridge said:
If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

22 20SleepFixSam, PurityPaulOR, MaxMetOK and 19 others
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SleepDoc_PDX
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Portland, OR
Apr 4, 2026 at 11:19 AM#32
raj_cambridge said:
If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

That reframing is the part I needed. Adding it to my notes with a link back to this thread.

Last edited: Apr 4, 2026 at 2:19 PM
23 21hank_denver, carlos_SATX, sophie_paris and 20 others
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Dr.GastroMayo
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Apr 8, 2026 at 8:51 PM#33

Clinical perspective, offered as context rather than as advice. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.

Last edited: Apr 9, 2026 at 1:51 AM
24 22COA_Karl, MikeFit_NJ, InsuranceTom and 21 others
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JessicaH_TX
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Apr 13, 2026 at 6:20 AM#34
Dr.GastroMayo said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

Same pattern here, and in the same order. I had assumed I was the exception until I read this.

25 23Dr.NephBHM_UK, kim_atl_prep, sarah_TO and 22 others
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kim_atl_prep
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Apr 17, 2026 at 3:47 PM#35
Dr.GastroMayo said:
Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third…

There is a second half to this that has not been said yet. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Last edited: Apr 17, 2026 at 9:47 PM
26 24PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 23 others
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