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ForumsSemaglutide (Ozempic / Wegovy)STEP 1-5 trials comprehensive summary — what worked for you? Page 6

STEP 1-5 trials comprehensive summary — what worked for you?

kevin_tulsa Mon, Feb 23, 2026 at 12:57 PM 32 replies 1,355 viewsPage 6 of 7
LindaRN_retired
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Mar 15, 2026 at 9:39 PM#26
TirzTom said:
Practical: whatever you change, write down the date and the reason.

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

29 2DataDave, Dr.GutHealth, amsterdam_pete and 26 others
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BrianDallas92
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Mar 18, 2026 at 11:08 AM#27
TirzTom said:
Practical: whatever you change, write down the date and the reason.

Bookmarking. The distinction being drawn above is the one nobody else makes. Taking it to my next appointment.

30 3mona_PHX, andrew_nyc, Dr.EndoEP and 27 others
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SarahChen_PharmD
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Mar 21, 2026 at 12:36 AM#28

Adding the clinical framing, because it changes how the question reads. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

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denise_HTX
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Mar 23, 2026 at 2:02 PM#29
SarahChen_PharmD said:
There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

This is my experience too, for whatever a second data point is worth.

32 5KevinCompounds, TirzTom, TrialTracker_MD and 29 others
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kevin_tulsa
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Mar 26, 2026 at 3:27 AM#30

OP back with an update, since a thread like this is useless without one.

Six weeks on from posting: I stopped reading the weekly number and started reading a four-week average, and the "stall" I opened this thread about was a 1.8kg loss I could not see.

4 2NurseLeah_Nash, gary_naperville, sean_dublin and 1 other
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