Dr.SportsMedIN said:Start from the measurement rather than the conclusion.
That holds for the injectable. The oral formulation has different absorption behaviour and the dose numbers are not interchangeable, which is worth saying out loud because people quote them as if they were.
DerekSJ_a1c said:The dose-response is real but shallow at the top.
This answered a question I did not know how to ask. Printing the relevant bit and taking it with me.
Dr.SportsMedIN said:Start from the measurement rather than the conclusion.
This is where I part company with the consensus forming above. The trial means are being read too generously in this thread. STEP populations were selected, supported, and titrated by protocol, and the real-world curves are consistently a few points worse. That difference is not noise, it is what happens when you remove the study infrastructure.
That is the short version; the long version is somebody else's post.
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Browse GL BiochemAdding the numbers, since they settle part of this. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.
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