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ForumsSemaglutide (Ozempic / Wegovy)Long-term semaglutide (3+ years) — member check-in thread Page 5

Long-term semaglutide (3+ years) — member check-in thread

mike_nyc Sat, May 30, 2026 at 10:03 AM 22 replies 376 viewsPage 5 of 5
stefan_berlin
Member
234
1,123
Oct 2024
Berlin, DE
Jun 4, 2026 at 12:37 PM#21

The figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Last edited: Jun 4, 2026 at 3:37 PM
40 13NeuroNate, JessicaH_TX, KevinCompounds and 37 others
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PharmHunterJen
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567
2,345
Jul 2024
Illinois
Jun 5, 2026 at 6:02 AM#22

One thing that is still open after BariatricNurseD’s answer:

What the dose-response curve actually looks like above 1.7mg, because the trial means hide how few people account for the extra loss?

41 14alex_tucson, kevin_tulsa, Dr.PainCLE and 38 others
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wendy_avl
Member
245
1,123
Oct 2024
Asheville, NC
Jun 5, 2026 at 11:28 PM#23
stefan_berlin said:
If you are going to change something, change one thing and give it long enough to express itself.

This is where I part company with the consensus forming above. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

42 15TomTeleRx, DoseLogDan, SleepFixSam and 39 others
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Dr.PainCLE
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6,234
Mar 2024
Cleveland, OH
Jun 6, 2026 at 4:54 PM#24
stefan_berlin said:
If you are going to change something, change one thing and give it long enough to express itself.

Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.

Last edited: Jun 6, 2026 at 7:54 PM
43 16bbq_ray_KC, oliver_london, tane_welly and 40 others
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steph_laguna
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Nov 2024
Laguna Beach, CA
Jun 7, 2026 at 10:21 AM#25
stefan_berlin said:
If you are going to change something, change one thing and give it long enough to express itself.

Saving this. It is the first explanation that did not require me to already understand it. I will report back once I have actually tried it.

44 17marco_milano, pam_columbus, nick_SD_fit and 41 others
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