From the other side of the consultation, briefly. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.
Dr.LeslieOBGYN said:Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…
This matches mine closely enough to be worth saying so out loud.
Dr.LeslieOBGYN said:Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…
There is a second half to this that has not been said yet. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.
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Browse GL BiochemOne concrete data point for the thread. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.
I would rather be corrected than agreed with, if it comes to it.
One thing that is still open after Dr.LeslieOBGYN’s answer:
How much of the between-person variation is pharmacokinetic and how much is just adherence measured badly?