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ForumsSemaglutide (Ozempic / Wegovy)Novo Nordisk supply chain update — semaglutide availability Q2 2026 Page 4

Novo Nordisk supply chain update — semaglutide availability Q2 2026

Admin Mon, Feb 26, 2024 at 4:00 PM 278 replies 41,224 viewsPage 4 of 20
MikeNYC_runner
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Mar 2, 2024 at 2:45 AM#16
chris_chi24 said:
Admin said: ...but the FDA says semaglutide...

Can confirm the pattern chris_chi24 describes. Albumin binding above 99% is the whole reason weekly dosing works, and it is also why the trough matters more than the peak. People who dose late are not losing a peak, they are letting the trough fall, and the appetite effect tracks the trough.

13 11PedsEndoPhilly, SleepDoc_PDX, RegAffairsDC and 10 others
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Dr.PeteFamMed
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Mar 2, 2024 at 12:50 PM#17
Dr.RaviCardio said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

There is a second half to this that has not been said yet. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

14 12tommy_boulder, hyun_seoul, jim_asheville and 11 others
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PeptideChemSF
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Mar 2, 2024 at 10:55 PM#18

Adding the numbers, since they settle part of this. Worth knowing that the injection site changes very little. Abdomen, thigh and upper arm are bioequivalent for semaglutide, so a site change is not a plausible explanation for a bad week.

Last edited: Mar 3, 2024 at 2:55 AM
15 13FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 12 others
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MASHdoc_SA
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Mar 3, 2024 at 9:00 AM#19

One thing that is still open after Dr.RaviCardio’s answer:

Whether anyone has held at a sub-maximal dose long term and kept the result, or whether the maintenance data only exists at 2.4mg?

16 14LabKate, kate.chem, DataDave and 13 others
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EndoResFellow
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Mar 3, 2024 at 7:04 PM#20

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here.

38 11Dr.ObesityLA, NurseKim_ATL, paul_denver and 35 others
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