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ForumsRetatrutide & Triple AgonistsRetatrutide kidney outcomes — anyone have experience? Page 3

Retatrutide kidney outcomes — anyone have experience?

NurseKim_ATL Thu, Mar 21, 2024 at 8:45 PM 40 replies 2,260 viewsPage 3 of 8
JessicaM_2024
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Mar 23, 2024 at 11:33 PM#11
traveltech_sara said:
The phase 2 numbers were about 24% mean weight loss at 48 weeks on the top dose, with the curve still descending at the end of the study.

This is exactly what I could not find anywhere else.

41 14james_edin, FranDenver, Dr.BariatricHTX and 38 others
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chris_chi24
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Mar 25, 2024 at 8:54 AM#12

From the other side of the consultation, briefly. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

42 15MounjBrad, nick_newbie, DadBodDave and 39 others
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PurityPaulOR
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Mar 26, 2024 at 6:15 PM#13
PeptideChemSF said:
FLOW is the relevant trial and it reported a meaningful reduction in kidney-disease progression and related death in people with type 2 diabetes and…

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

Last edited: Mar 26, 2024 at 9:15 PM
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kate.chem
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Mar 28, 2024 at 3:35 AM#14

Adding the numbers, since they settle part of this. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

Last edited: Mar 28, 2024 at 6:35 AM
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mike_mod
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Mar 29, 2024 at 12:54 PM#15

Moderator note: a couple of off-topic posts removed. Tagging this one for the weekly digest.

45 18PurityPaulOR, MaxMetOK, MounjBrad and 42 others
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