Dr.AddMedPHL said:The distinction that resolves most of these threads is between what is true on average and what is true for one person.
That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.
Dr.PulmRoch said:The phase 2 numbers were about 24% mean weight loss at 48 weeks on the top dose, with the curve still descending at the end of the study.
Thank you for spelling out the reasoning rather than just the conclusion. Taking it to my next appointment.
Dr.AddMedPHL said:The distinction that resolves most of these threads is between what is true on average and what is true for one person.
This is where I part company with the consensus forming above. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.
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Browse GL BiochemAdding the numbers, since they settle part of this. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.
If somebody has the primary source to hand I would rather cite it than paraphrase it.
Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Carry on.