Adding the clinical framing, because it changes how the question reads. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.
Correct me if the detail matters more than I have assumed.
Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.
If somebody has the primary source to hand I would rather cite it than paraphrase it.
GenomicsKate said:The mechanism and the magnitude are separate questions.
Second this.
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Shop Reference StandardsGenomicsKate said:The mechanism and the magnitude are separate questions.
Coming at GenomicsKate’s question from a different direction. Most of what circulates confidently in this community traces back to one summary of one study, and the qualifier was dropped somewhere in the third retelling.
Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Tagging this one for the weekly digest.