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ForumsRetatrutide & Triple AgonistsTRIUMPH-2 obesity without diabetes — anyone have experience? Page 2

TRIUMPH-2 obesity without diabetes — anyone have experience?

Dr.ObesityLA Wed, Apr 16, 2025 at 8:08 AM 23 replies 1,941 viewsPage 2 of 5
lisa_labSD
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Apr 17, 2025 at 8:37 PM#6

One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

10 5stefan_berlin, Dr.EM_Chicago, pete_RVA and 7 others
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TomFromTexas
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Apr 18, 2025 at 11:13 AM#7

One thing that is still open after TinaHashiRN’s answer:

What the phase 2 dropout pattern implies about how the phase 3 tolerability will read?

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PeptideChemSF
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Apr 19, 2025 at 1:49 AM#8
lisa_labSD said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Coming at lisa_labSD’s question from a different direction. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

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Dr.ObesityLA
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Apr 19, 2025 at 4:25 PM#9

Closing the loop on my own question.

Rereading it with the dropout table open changed my view. I still think it is the most interesting molecule in the pipeline; I no longer think the 24% is the number that will end up on a label.

Last edited: Apr 19, 2025 at 5:25 PM
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LindaRN_retired
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Apr 22, 2025 at 2:33 PM#10
PeptideChemSF said:
Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…

True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

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