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ForumsRetatrutide & Triple AgonistsGlucagon-mediated thermogenesis on retatrutide — looking for input Page 4

Glucagon-mediated thermogenesis on retatrutide — looking for input

SkepticalSean Sat, Jun 14, 2025 at 8:51 AM 17 replies 1,657 viewsPage 4 of 4
Dr.NutriCornell
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Jun 18, 2025 at 4:58 AM#16

Clinical perspective, offered as context rather than as advice. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

30 3emily_PDX, Dr.SleepRoch, laura_annarbor and 27 others
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hannah_MT
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Jun 18, 2025 at 5:40 PM#17
Dr.NutriCornell said:
If two explanations both fit, the useful question is which one predicts something the other does not.

This is where I part company with the consensus forming above. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

Last edited: Jun 18, 2025 at 8:40 PM
31 4MounjBrad, nick_newbie, DadBodDave and 28 others
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JessicaM_2024
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Jun 19, 2025 at 6:22 AM#18
Dr.NutriCornell said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Correct as far as it goes. The part it does not cover is what to do when the honest answer is "not enough data", which is more often than anyone likes.

32 5mike_mealprep, NicoleRaleigh, james_edin and 29 others
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claudia_zurich
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Jun 19, 2025 at 7:04 PM#19
Dr.NutriCornell said:
If two explanations both fit, the useful question is which one predicts something the other does not.

Thank you — that is the clearest version of this I have read, and I have read a lot of them. Printing the relevant bit and taking it with me.

33 6alex_tucson, kevin_tulsa, Dr.PainCLE and 30 others
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mike_mod
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Jun 20, 2025 at 7:46 AM#20

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Carry on.

5 3PurityPaulOR, MaxMetOK, MounjBrad and 2 others
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