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ForumsTirzepatide (Mounjaro / Zepbound)Has anyone dealt with tirzepatide dual agonism: gip + glp-1 synergistic mechanism? Page 5

Has anyone dealt with tirzepatide dual agonism: gip + glp-1 synergistic mechanism?

robert_kc Fri, Apr 5, 2024 at 12:28 AM 49 replies 2,765 viewsPage 5 of 10
pat_auckland
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May 5, 2024 at 1:05 PM#21

Clinical perspective, offered as context rather than as advice. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Last edited: May 5, 2024 at 5:05 PM
37 10NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 34 others
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HPLC_Greg
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May 16, 2024 at 11:43 PM#22
pat_auckland said:
The mechanism and the magnitude are separate questions.

Same pattern here, and in the same order. Posting only so the count is not one.

Last edited: May 17, 2024 at 5:43 AM
38 11JenPlateau, SallyK_inj, CryptoCarl and 35 others
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PurityPaulOR
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May 28, 2024 at 10:14 AM#23
pat_auckland said:
The mechanism and the magnitude are separate questions.

Adding the part of the answer the thread has not reached. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

39 12Admin, Dr.Martinez, mike_mod and 36 others
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NicoleRaleigh
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Jun 8, 2024 at 8:39 PM#24

The figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

40 13VendorMark, COA_Karl, MikeFit_NJ and 37 others
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tom_AK
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Jun 20, 2024 at 6:57 AM#25

One thing that is still open after pat_auckland’s answer:

How would you tell the difference between that and the alternative explanation?

Last edited: Jun 20, 2024 at 10:57 AM
41 14Dr.RaviCardio, jennifer_SEA, tyler_CSCS and 38 others
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