Clinical perspective, offered as context rather than as advice. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.
One thing that is still open after NicoleRaleigh’s answer:
What would you measure differently if you were starting again?
paige_pharma said:Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…
Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
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View Resultspaige_pharma said:Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…
Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.
Ask again with the specifics and you will get a better answer than this one.