Reta hype is insane but I am cautiously optimistic

Dr.AddMedPHL said:

The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.

MikeFit_NJ said:

The glucagon component looks paradoxical and is not.

This is exactly what I could not find anywhere else. Sending this to two other people who asked me the same thing last week.

Dr.AddMedPHL said:

The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

This is where I part company with the consensus forming above. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

Happy to go further on any of that.

Adding the numbers, since they settle part of this. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

Moderator note: a couple of off-topic posts removed.