FLOW trial: semaglutide renal outcomes — anyone have experience?

From the other side of the consultation, briefly. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

Worth separating that from semaglutide, which this thread keeps folding into the same question. They behave differently and the advice does not transfer.

Dr.GutHealth said:

The distinction that resolves most of these threads is between what is true on average and what is true for one person.

Second this. Posting only so the count is not one.

Dr.GutHealth said:

The distinction that resolves most of these threads is between what is true on average and what is true for one person.

Adding the part of the answer the thread has not reached. The version of this that has an answer is narrower than the version being asked. Narrow it and it becomes tractable; leave it broad and the thread will produce nine confident and incompatible replies.

One concrete data point for the thread. Worth knowing that the injection site changes very little. Abdomen, thigh and upper arm are bioequivalent for semaglutide, so a site change is not a plausible explanation for a bad week.

That is the short version; the long version is somebody else's post.

Following on from Dr.GutHealth — and this may be the naive question:

What the dose-response curve actually looks like above 1.7mg, because the trial means hide how few people account for the extra loss?