Can we talk about how SLOW the FDA is — my results so far

PharmacoVig_BOS said:

Propensity score matching studies and the trial evidence: when RCTs aren't available for a specific question, propensity score-matched observational…

Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.

jason_paloalto said:

DebRD_ATL said: ...regarding the trial evidence...

Bookmarking. The distinction being drawn above is the one nobody else makes.

PharmacoVig_BOS said:

Propensity score matching studies and the trial evidence: when RCTs aren't available for a specific question, propensity score-matched observational…

I read this differently from PharmacoVig_BOS, on substance rather than tone. Pushing back on the anecdote-stacking. Twenty people reporting the same thing is twenty samples from the same self-selected pool, not twenty independent confirmations.

Ask again with the specifics and you will get a better answer than this one.

One concrete data point for the thread. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

Moderator note: the sourcing question belongs in the vendor section and has been split out.