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ForumsLab Results & BiomarkersVitamin B12 monitoring — 6 month update

Vitamin B12 monitoring — 6 month update

emma_london Tue, Mar 10, 2026 at 1:40 PM 8 replies 769 viewsPage 1 of 2
emma_london
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Mar 10, 2026 at 1:40 PM#1

I started taking a multivitamin as insurance and then found out that two of the things I was actually short of were the two it barely contains.

The bit I cannot resolve on my own is which deficiencies actually show up when intake drops this far, and which are worth testing rather than supplementing blind.

I have searched first, so if this is covered somewhere point me at it and I will read it.

48 1sarah_nash92, FitDadDave, RunnerRach and 45 others
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BariatricNurseD
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Mar 10, 2026 at 2:02 PM#2
emma_london said:
I started taking a multivitamin as insurance and then found out that two of the things I was actually short of were the two it barely contains.

Blood count monitoring for micronutrients: my doctor noticed my MCV (mean corpuscular volume) trending up at month 6: 90 → 97 fL. This flagged potential B12 or folate deficiency.

Sure enough, B12 had dropped from 620 to 340 pg/mL. Started B12 injections monthly and MCV normalized within 2 months. GLP-1 agonists can impair B12 absorption — this is a real clinical concern that deserves routine monitoring.

49 2roxy_nash, tony_orlando, Dr.NephBHM_UK and 46 others
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oliver_london
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Mar 10, 2026 at 2:24 PM#3
BariatricNurseD said:
Blood count monitoring for micronutrients: my doctor noticed my MCV (mean corpuscular volume) trending up at month 6: 90 → 97 fL.

Vitamin and mineral labs to check while on micronutrients — my doctor orders these quarterly:

  • B12: Can drop due to reduced GI absorption. Mine went from 650 to 380 — now supplementing.
  • Iron/Ferritin: Reduced food intake = reduced iron. Ferritin dropped from 73 to 30. Supplementing.
  • Vitamin D: Was already low (20 ng/mL), now taking 5000 IU daily.
  • Folate: Stable, no issues.
  • Zinc: Slightly low, added a multivitamin with zinc.

Nutritional deficiencies are a real risk when you're eating significantly less. Don't skip your labs!

50 3Dr.LeslieOBGYN, MikeNYC_runner and 47 others
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SkepticalSean
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Mar 10, 2026 at 2:46 PM#4
emma_london said:
I started taking a multivitamin as insurance and then found out that two of the things I was actually short of were the two it barely contains.

Mine went the same way, slower.

Last edited: Mar 10, 2026 at 6:46 PM
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traveltech_sara
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Mar 10, 2026 at 4:46 PM#5

Clinical perspective, offered as context rather than as advice.

Iron studies on micronutrients — important especially for women:

MarkerBaselineMonth 6After Supplementation
Ferritin612451
Iron915684
TIBC316386336
Transferrin Sat34%16%25%

My ferritin cratered at month 6 from reduced dietary intake. Iron bisglycinate 36mg with vitamin C brought it back up. Don't wait for anemia symptoms — test proactively.

Last edited: Mar 10, 2026 at 7:46 PM
2 5BenResearch_OR, MikeKY_noInsulin
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